Pulmonary Embolism Essay Example | Topics and Well Written Essays - 1000 words

Pulmonary Embolism - Essay Example The clots can break free, travel to the lung, and block an artery. The condition can uncommonly be caused from fat escaping from fractured bone marrow or from amniotic fluid during childbirth. With a large clot, or many number of clots, pulmonary embolism can cause death. The process by which a pulmonary embolism forms, begins in the blood stream. Blood flows from the right side of the heart to the lungs where it picks up oxygen. The heart pumps this oxygen-rich blood through arteries delivering it to various parts of the body after which it enters another network of veins. The veins carry the now oxygen-poor blood back to the heart, which pumps the blood to the lungs to pick up oxygen again. A blood clot forming in a vein, commonly a deep vein in the leg, can travel with the blood flow back to the lungs and become lodge there.This leads to pulmonary embolism. When the lung arteries become blocked by a blood clot, high blood pressure in the lungs may occur. This results in the heart having to pump harder than usual. A continually overworked heart may enlarge and may eventually fail to function. A large pulmonary embolism can result in failure of both the lungs and heart. However, the sooner a physician can diagnose and treat the condition, increases the chances of surviving a pulmonary embolism. The symptoms of pulmonary embolism differ widel... The symptoms of pulmonary embolism differ widely and often resemble those of other conditions; the classic signs include sudden shortness of breath, chest pain and a cough that produces blood-streaked sputum. Breathing may be very rapid and breathing deeply may cause severe chest pains. Other symptoms include increased pulse rate, dizziness, and fainting. Pulmonary infarction may result if there is a lack of blood flow to the lungs causing some lung tissue to die. In addition the patient may also cough up blood-stained phlegm, have sharp chest pains, and fever. The skin may turn a bluish color from a lack of oxygen when the larger vessels of the lungs are blocked. Chronic pulmonary embolism, where small blood clots deposit themselves in the lungs repeatedly over time, will cause shortness of breath, swelling of the leg and all round weakness (MayoClinic 2006). Risk factors for a pulmonary embolus include: Prolonged bed rest or inactivity (including long trips in planes, cars, or trains), Oral contraceptive use, Surgery (especially pelvic surgery), Childbirth, Massive trauma, Burns, Cancer, Stroke, Heart attack, Heart surgery, Fractures of the hips or femur A blood clot is the first factor towards pulmonary embolism and one that forms in a vein is called a thrombus. A blood clot is a plug of platelets enmeshed in a group of red blood cells and fibrin. Blood clots usually develop to help stop bleeding an injury, but sometimes form without reason. A clot that develops in one part of the body and travels in the bloodstream to another part of the body is called an embolus. Sometimes other substances, such as pieces of a tumor, globules of fat from fractured bones or air bubbles, may enter the bloodstream and become an embolus that blocks arteries. A vein in the leg or

SGT Rome award Essay Example | Topics and Well Written Essays - 250 words

SGT Rome award - Essay Example His unparalleled ability to multi-task and achieve outstanding results were truly invaluable to daily operations in the detachment. SGT Rome effectively demonstrated strong leadership and sound judgment on assignments by coordinating and advising the Commander on measures of efficiency and effectiveness on all products and product concepts. SGT Rome in many ways was the glue that bonded the three teams to remain cohesive for the purpose of accomplishing their mission. He is a person who can be relied upon and works without supervision. SGT Rome’s dedication to the mission and unwavering passion for his soldiers is an attribute that cannot be denied. His actions are in keeping with the finest traditions of the military service and reflect distinct credit upon himself, the nation and the United States army. Bibliography Hastings, M. (2011) â€Å"Another Runaway General: Army Deploys Psy-Ops on U.S. Senators†. Rolling Stone

Global Marketing Essay Example | Topics and Well Written Essays - 3750 words

Global Marketing - Essay Example This research will begin with the statement that organizations, which are operating in any industrial sectors including in the sector of Information Technology (IT), would want to expand their operations into foreign territories due to various factors. That is, organization could think about entering foreign markets if they have achieved optimal success in the home market, or due to heightened competition or saturation in the home market, or due to good opportunities in the foreign market, etc, etc. Whatever is the motivation for the firms to enter foreign territories, it is paramount on the part of the organization to study the foreign market in an in-depth as well as extensive manner. Various factors will be at ‘play’ in those foreign markets, and those factors will either aid the entering organization or will pose a major challenge to the organization. These factors will be visible both in the macro as well as in the micro environment of the organization. In the macro -environment, factors including political, social, cultural, economic, etc., could impact the entering organization. In the micro or in the immediate environment of the firm, market factors including competitors, recent trends, etc., will impact the organization. After analyzing these factors, the firms have formulate a set of objectives, so they have can have a clear path, regarding what to achieve and how to achieve those objectives. The next key process is analyzing the various entry modes and finding out the best entry mode. The firms should also plan out the marketing strategies that have to be implemented in the entering countries before-hand, so they can aptly reach their products or services to the intended customers. All these key processes will be applicable to our software development firm as well. Our company is a medium sized software firm developing software for applications in many sectors particularly electronics and communications sector. In our home operations in U K, we have around 2000 employees working in our various offices in number of cities. We are achieving optimal success and good profits in the UK market, but still some competition is emerging. Although, we can aptly fight the competition, with the intention to grow further, we are looking at foreign expansion. So, after achieving great success in the UK market, our firm has decided to broaden our horizons and target, initially the two foreign markets of Brazil and India. This report will first do an environmental audit of both the countries through the PESTEL and Porter’s Five Forces tool, and by focusing on the market as well as the competitors. Secondly, the report will set the SMART global marketing objectives for going international, then will discuss about the entry modes, finally ending with the discussion about the marketing strategies that has to be implemented for optimal success. Environmental Audit Every market or country including Brazil and India has certain uniq ue or common political, social and economic conditions, along with different clients’ base, consumer behaviour and competitors. These distinct aspects could aid as well as impede the organisations’ entry into that particular market as well as the resultant success. So, understanding and analyzing these aspects behaviour in relation with the product or service is a key necessity. Based on this analysis only, the marketing strategies need to be formulated, so that organisation can reach maximum customers, entice them and importantly build long-term relationship, thereby retaining them. As the above mentioned country specific aspects need to be mainly analyzed in relation with the product that is going to be launched, the product’s profile should ‘fit’ with the consumer of that particular market. Although, it applies to all product range, it is of utmost importance to the firms dealing in the IT sector. So, from the above understanding, it is clear tha t, the macro and the micro environment for the software firms as well as the consumer behaviour in the Brazilian and Indian market has to be analyzed, based on

Multiple Intelligence Theory Essay Example for Free

Multiple Intelligence Theory Essay Many students choose to attend APUS because the University fosters differing educational styles and empowers the students through education. The Student Handbook states, â€Å"The University System fosters an environment that promotes a life of learning for its constituents and uses feedback from its participants and supporters to improve the quality of its teaching, learning, and support†¦ The University System anticipates and adapts to its changing environment and responds to the needs of the organization and its constituencies in manners both appropriate and timely. † In the beginning of College 100, students are introduced to the different learning styles and the theory of multiple intelligences. By becoming familiar with other students learning styles and exploring the multiple intelligences students became more tolerant towards others and were able to strengthen their learning power. Being familiar with multiple intelligence theory, knowing the different learning styles, utilizing appropriate classroom methods, and exploring the interdisciplinary classroom will empower students towards a lifetime of learning. Recognizing the multiple intelligence theory is the first step in capturing the different learning styles. â€Å"Howard Gardners multiple intelligence theory (Gardner, 1993) proposes the idea that we all have various levels of intelligence across a range of intellectual areas† (Pritchard, 2008). The concept that people learn in different ways, and perceive and learn by different methods is what makes up the theory of multiple intelligences. There are at least nine different intelligences in which people display in varying ways (Pritchard, 2008). The styles are as follows: linguistic, logical/mathematical, musical, spatial/visual, kinesthetic, interpersonal, intrapersonal, naturalistic, and existential (Pritchard, 2008). Student’s particular academic strengths have a direct impact on how effective their learning will be for their overall education. When applying multiple intelligences to the classroom, it is very important to cater to all the types of learning styles. When discussing learning styles in the forums of College 100, every student had a different way of learning that especially worked for them. If every single assignment or activity in a classroom is slanted towards visual learning, then the students who are auditory or kinesthetic learners will be at a serious disadvantage. These students will not be able to express themselves or be able to conform to the teaching style if their learning needs are not met. â€Å"In planning for multiple intelligences, teachers consider the range of activities related to the content of the lesson and the intended learning outcomes will give a range of opportunities to the children’s different intelligence strengths† (Pritchard, 2008). It is very important for a teacher to introduce a range of activities and presentations in order to make the most out of multiple intelligences. A learning style is reflected by a students preferred method of learning, which is a direct result of their type of intelligence. It is irresponsible for a teacher to assume that all of their students will learn in the same manner. The four main styles of learning are visual, auditory, kinesthetic, and extrovert. Every style has strengths and weaknesses. It is crucial in the educational environment to exploit the student’s strengths and protect the weaknesses. A student’s self-worth and esteem can be very much tied up with their learning capability. Teachers must exhibit a range of teaching styles, so that their students learning styles will be compatible. â€Å"Diverse personalities impact relationships, motivation, and ease of learning in classroom and work environments. Where there are diverse personalities within groups, people generally prefer and choose to be with others who are similar to themselves; individuals may even dislike those who have different attitudes and behaviors from their own† (Richardson Arker, 2010). What Richardson and Arker are implying is that people of different personalities and learning styles tend to stick in the same groups. It would be to the benefit of everyone if individuals of different personalities and persuasions were put together in one group, that way the group will be more powerful and will benefit greatly from the input of everybody. A truly good teacher will ensure that they have designed their curriculum in such a way so that students learning needs are met. Classroom arrangements can be made so that individuals of similar temperaments are brought together in what is called compatibility scheduling. This arrangement will enhance the overall productivity of students as well as teachers† (Richard son Arker, 2010). As multiple intelligence theory has developed, advances in classroom methods have also been made. There are at least three different methods that combine multiple intelligence theory with learning styles in order to better the classroom environment. â€Å"Brain-based education supports the need to differentiate instruction† (Richardson Arker, 2010). Some studies in brain research have shown that there is such a thing as a left-brain and a right-brain. People can be left or right brain dominate, which largely determines the individuals learning style. â€Å"Collaborative learning is a method of teaching and learning in which student’s team together to explore a significant question or create a meaningful project† (Educational Broadcasting Corporation, 2004). This type of classroom learning will serve to help the entire group. The students and teachers will be able to pick out the roles that suit them best, thus serving the group to the best of their ability. Another method that is similar to collaborative learning is cooperative learning. In cooperative learning, â€Å"Students work together in small groups on a structured activity. They are individually accountable for their work, and the work of the group as a whole is also assessed. Cooperative groups work face-to-face and learn to work as a team† (Educational Broadcasting Corporation, 2004). Cooperative learning is becoming a very popular method. It uses individuals best qualities for the betterment of the group. By using these methods in the classroom learning becomes an active process and engages all types of learning styles. The Western world has divided education into blocks, and then further divided the blocks into disciplines. While convenient on paper, it is clear that education and disciplines overlap, the world is a fluid place. Interdisciplinary education is an approach that blends different disciplines and utilizes multiple intelligence theory and varying learning styles. â€Å"The exponential growth of knowledge in the twentieth century revealed how disciplinary cultures and perspectives could discourage inquiries and explanations that spanned disciplinary boundaries. Disciplines, it now seems clear, are powerful but constraining ways of knowing† (Lattuca, 2001). By breaking down the walls of the disciplines, students are empowered to use their differing learning styles. This will result in students having positive experiences with education. Students will then seek out a lifetime of learning, and encourage other to seek knowledge. Recognizing the theory of multiple intelligences and defining each student’s learning style will lead to success in education. By utilizing methods such as brain-based learning, cooperative learning, and collaborative learning teachers can empower students by giving them the educational method that works best for each individual. Combining all of these aspects yields the concept of interdisciplinary learning, leading to a lifetime of successful education, teaching, and learning. References Concept to Classroom: Course Menu. (2004). THIRTEEN New York Public Media. Retrieved December 2, 2012, from http://www.thirteen.org/edonline/concept2class/index.html Lattuca, L. R. (2001). Creating interdisciplinarity: Interdisciplinary research and teaching among college and university faculty. Nashville: Vanderbilt University Press. Pritchard, A. (2008). Ways of Learning [electronic resource]: Learning Theories and Learning Styles in the Classroom. Hoboken, NJ: David Fulton Publishers. Richardson, R., Arker, E. (2010). Personalities in the Classroom: Making the Most of Them. Kappa Delta Pi Record, 46(2), 76-81.

Minds Are Opened Only When Hearts Are Opened Essay Example for Free

Minds Are Opened Only When Hearts Are Opened Essay â€Å"Minds are like parachutes. They only function when they are open.† James Dewar To create the life that you want, growing as a human being and regularly experiencing a prosperous lifestyle, you will need a mind open to other people, possibilities, ideas and opinions around you. When you have an open mind you allow yourself to attract and follow up on opportunities. When you work with the power of the conscious and subconscious mind you will attract opportunities that will bring you what you need; for what you radiate you will constantly attract. When you are prepared to become creative you will create a vibrant life, while eliminating negative and unwanted situations. Most people think they already listen to others with an open mind, merely by paying close attention to what is being said. In fact, keeping an open mind is not easy to do if you are happy with the way you are doing things and do not see the point of changing. We all have moments, however, when we do listen with an open heart and mind, for example, we are more open to listening to someone we trust. An open mind is an understanding mind which will develop a genuine appreciation for people. When you take the trouble to think of other people’s feelings, their viewpoints and their desires you are saying â€Å"people are important†. An open mind will accept other people unconditionally. It requires the letting go of likes and dislikes and other similar emotions. When you do this you discipline your emotions and you allow people to be who they are with all their idiosyncrasies, differences and irritations. When you are communicating with others there can often be misunderstandings and these can lead to failure in your relations with others. We expect others to react and respond and come to the same conclusions we do over a given set of facts. Unfortunately, no one reacts to things as they are but to their own mental images; they are responding appropriately to what they see as the truth about the situation. An open-minded person will ask themselves â€Å"How does this appear to that person?† or, â€Å"How does that person interpret the situation?† and they will try to understand why someone might act differently to the way they expected. Many small business owners have faced extinction because they thought they knew it all and were not prepared to have an open mind and listen to others who had been down that path before them. When you are open minded you are always prepared to be teachable, to learn something new and take advantage of opportunities that present themselves. An open mind is the doorway to expansion of ideas. When you open your mind you are not compromising your ethics and values. It just means that you begin to practice a greater sense of awareness and in doing so you are prepared to look at your world a little differently. Test opportunities that are presented to you and examine where the message is coming from. It may be from a friend, a neutral party or from a source about which you are sceptical. If you are not sure, instruct your subconscious mind to guide you by simply saying, â€Å"I am making the right decision.† Focus on what you want, not on what you don’t want. A Closed Mind â€Å"A closed mind is like a closed book; just a block of wood. – Chinese Proverb. We have all been given the power to develop ideas and exercise free will. Unfortunately too often those ideas die as a seed and people use their free will to close their mind to the tremendous opportunities surrounding them. This stubbornness prevents them from achieving the goals that they want for themselves and so the opportunity for success is greatly decreased. In our formative years we grow and develop egos that maintain very particular ideas about ourselves in relation to the world around us. Your ego is your conscious mind, that which controls your behaviour and tries to give meaning to your external, material reality. It is powerful and can control your life if you allow it. Your external reality is a direct result of your mental and spiritual self so if the latter two are not where you want them to be your external and material self will suffer. The ego cannot improve the quality of your mental and spiritual life. When you close your mind you essentially become stubborn and become a victim of the ego mind which says, â€Å"My attitude is right despite what anyone else has to say†. The ego mind, although it thinks it knows better than anyone else, is never prepared to leave its comfort zone and so is not open to new ideas nor will it welcome others into its world. This kind of attitude shuts you off from the process of life and nature which is about growing and experiencing new possibilities. Think about how many times you were resistant to trying something new only to eventually give in and discover that you really enjoyed the process. Limitations are the jail of the mind so if you can throw off the shackles and open your mind to new and exciting ideas, your possibilities become limitless. When the mind is shackled and limited it affects every part of your life, for example, work presentations can lack innovation and impact and even every-day conversations are less productive and rewarding. Conversations often become defensive as the mind closes off to what is being said by others. Society today gives out a negative message that everyone is out to ‘take you down’ and that if it ‘looks to good to be true, it probably is’. This causes many to close their minds to everything beyond their current knowledge. An open mind is a mind that is aware that the current knowledge is not all there is to know and will eagerly investigate possibilities. When you have a closed mind to new and exciting possibilities you essentially tell yourself that you are not willing to go the extra mile – that you are not willing to grow and experience new things. You have now switched off the power within you and there can be no change and no progress in life and things will never improve. Such people become very introspective and weak. The old recordings of the past can, however, be changed. If you choose, you can wipe the old record clean, put on a new record and make a decision to activate the positive thoughts which lead to a relaxed and open view of the world. Remember, the past explains how you got to the present but where you go from here is your responsibility. In his book A Vision of Power Glory, John Kehoe gives a Zen parable about two monks who are on a journey together when they come to a river. By the river there is a beautiful woman. The woman asks them, â€Å"Please will one of you monks carry me across the river? The river is too wide and the current too swift.† The two monks look at one another, because they have taken a sacred vow to not so much as even touch a woman. Then, abruptly, the older monk picks up the woman, carries her across the river and puts her down on the other side. They continue on their journey. The younger monk is flabbergasted. He can’t believe it. An hour goes by and not a word is spoken between them. Two hours. Three hours. And finally, after four hours, he turns to the older monk and blurts out, â€Å"How could you have done that? How could you have carried that woman?† â€Å"Oh?† responds his companion, â€Å"Are you still carrying her? I put her down four hours ago.† John Kehoe goes on to say, â€Å"How much are we still carrying around inside us that should have been put down a long time ago? Disappointments; regrets; failures; grudges. How much junk are we carrying around inside us and how long are we going to carry it? All our life?† If you want to change and improve your attitude to life then it is imperative that you keep an open mind. That is not to say you will be taken in by every ‘fly-by-night’ scheme that may be put before you. An open mind is curious and investigative and examines new things. Your creative power system uses your conscious and subconscious mind to attract, explore and check out new opportunities so that you can begin achieving your goals and creating the life you want. Don’t limit yourself; learn how to attract new possibilities and make the right decisions by developing the power of your mind and heart. If you move in your community with an open mind and an open heart you can learn to accept others. You don’t have to agree with them, but accept who they are and feel free to express yourself. I remember a friend of ours who has passed on now, who was well-known and well-liked in community affairs. He met many people as he moved around and sometimes in a gathering he would be heard to say, â€Å"There’s a fellow over there I met recently and I didn’t like him; I must go over and get to know him better†. He would always come away with a new-found friend; now that’s an open mind and open heart.

Impact of Demand and Supply Forces in the Market

Impact of Demand and Supply Forces in the Market In general, equilibrium market price is determined by where quantity demanded meets quantity supplied. This holds true for the property market in the UK, where prices are being driven by large demand for housing and an almost fixed supply of property. This larger demand of housing over existing supply has been the main factor driving UK property prices up in the last 10 years. However, these increased prices cannot last forever, the market (through changes in supply and demand, as well as government intervention) will find a new equilibrium due to factors that will bring demand down again. According to demand and supply theory, for a downward sloping demand curve, as price increases, quantity demanded moves leftward along the demand curve, resulting in a lower quantity demanded. On the other hand, in an upward sloped supply curve, as price increases, then quantity supplied moves rightwards along the supply curve for a higher quantity supplied. In the case of the UK housing market, let’s suppose we had a downward sloping demand and upward sloping supply, which intersected at P0 and Q0. About 10 years ago, the UK economy was starting its upwards growth cycle. This gave people more money which they could freely spend on purchasing property, increasing demand for housing. This increased demand caused the demand curve for property to shift outwards from D0 to D1. With this increase in demand, and the same supply curve S0, prices would have increased from P0 to P1 and quantity demanded and supplied would have increased from Q0 to Q1. However, this increase in demand which caused higher prices would also affect supply, so more builders and developers would want to construct housing in order to fulfil this growing demand. Yet, this increase in supply is always smaller than the increase in demand because of resource constraints—where will you actually build new housing and the time it takes to build such once you have found a place to do so and also because the builders know that others will be building too and so the increased price will not be as high as they initially saw. In the end, the total increase in supply is smaller than the increase in demand. This increase in supply (which takes a bit longer to be reflected in the market than the increase in demand) would imply an outwards shift of the supply curve from S0 to S1. This in itself would then reduce prices from P1 to P2 and increase quantity even more from Q1 to Q2. Since the increase in supply is not enough to offset the increase in demand, the cycl e begins again with another outward shift in demand, since those demanding Q2 at the lower price P2 are willing to pay up to P3, driving demand out again and helping the boom in housing prices. In reality, this increased demand and supply is continuously occurring and the process cannot be explained by the diagrams above. Some believe that part of the real reason why prices are so high right now is because people are buying based on how prices have been behaving and are not arbitraging: instead of correcting each others mispricing, they reinforce it. (Farlow 2004) However, in the future, demand for housing could become lower than supply, which would mean that prices would go down. Given the high prices to date, more developers are building new housing which would imply that supply is increasing. If this continues or even grows, then supply could at one point exceed demand, driving prices downwards. This is unlikely, as when builders are making decisions as to whether or not create new homes they factor in the supply of housing being built by their competitors, which sometimes causes the overall growth in supply to be lower than what some expected. Another factor that could influence a price crash is an economic recession, whereby many people are laid off and their disposable income is reduced. Were this to happen, then demand for property would decline, and again, prices would have to reduce to accommodate the lower demand. A third factor that could influence is if the government increased interest rates dramatically. In this case, the increas e in interest rates would result in two main issues: reducing consumer spending, which would include buying property, in favour of saving money, as savings rates would increase, and secondly, a reduction of people wanting to borrow money for properties, as mortgages would go up. This two-way reduction would also reduce demand for property, with a result of a reduction in property prices. As we have seen above, demand and supply forces can be used to explain how it is possible to get such a continued increase in the prices of UK housing over the last 10 years, beginning with a strengthening of the economy which injected cash into the market. This led to increased demand for housing which was not offset by identical increase in supply, which combined with continued economic growth and low interest rates just continued putting upward pressure on demand for housing and thus increasing prices. There have been many recent articles wondering when this upwards spiral will end but it is difficult to predict. The Bank of England has been trying to intervene by increasing interest rates in the last few months with yet another increase predicted in the near future, but this is not reflecting in a reduction for housing demand. A big factor that could help reduce property prices is a reduction in the overall economy, as occurred in the 1980s, when unemployment hit certain areas an d many were left with little income for buying homes. This, however, does not seem likely, given the pressure to maintain the economic boom. However, there will come a point when the majority of people will be unable to afford any housing due to its continuous price increases, driving demand for housing down. REFERENCES Farlow, A., 2004, â€Å"Part two: The UK Housing Market: Bubbles and Buyers†, Credit Suisse First Boston. Lipsey, R.G. and K.A. Chrystal, 1999, Principles of Economics, 9th edition, Oxford: Oxford University Press.

Alzheimers Disease and Downs Syndrome Essay -- Downs Syndrome Triso

Alzheimer and Down's Syndrome Down?s Syndrome, Trisomy 21, or Mongolism is one of the most common causes of mental retardation. The majority of Down?s Syndrome patients have a moderate retardation although it can range from mild to severe. Trisomy 21 occurs in about 1 in 800 live births. This incidence increases markedly as the age of the mother increases over 35. The prevalence in children born to young mothers is 1 in 1000, while it increases to almost 1 in 40 in children born to mothers over 40. Most individuals with Down?s Syndrome have characteristic features such as upward slanted eyes, broad flattened face, short neck, and a prominent tongue. Muscle coordination is often impaired in these individuals, resulting in uncoordinated posture and balance. Congenital heart disease is found in forty percent of these individuals, along with a near twenty fold increase in the risk of kidney malformation, thyroid abnormalities, diabetes, leukemia. Neurological retardation and impaired immune systems render these indiv iduals more susceptible to infection and disease. In the early l900s, Downs Syndrome patients rarely lived to reach the age of twenty, as they only had a life expectancy of about 10 years. With the advances of modern health care, most individuals, excluding those with irreparable heart damage, live to reach adulthood. Although it is still shorter than normal adults, their life expectancy has increased to about fifty-five. The disorder was initially described as Mongolism by British physician John Langdon Down. Many theories for the etiology of this condition surfaced, including racial regression, endocrine gland dysfunction, and uterine exhaustion. It was not until the 1930s that Adrian Bleyer hypothesized tha... ...e of ALZ-50 reactive neurons and the formation of senile plaques. Journal of the Neurological Sciences, 1992, 109: 593-598. Raghavan, R. Detection of Lewy Bodies in Trisomy 21. Can. J. Neurol. Sci., 1993, 20:48-51. Goodison. Neuronal and Glial Gene Expression in Neocortex of Down?s Syndrome and Alzheimer Disease. Journal of Neurol. and Exp. Neurol., 1993, 52 (3) 192-198. Hyman, B. T. Down Syndrome and Alzheimer disease. Prog. Clin. Biol. Res., 1992, 379: 123-42. Silverman W. Alzheimer neuropathology in mentally retarded. Acta Neuropathol. Berl., 1993, 85(3):260-6. Beyreuther, K. Regulation and expression of the Alzheimer?s Beta amyloid protein in Down?s Syndrome. Ann. N.Y. Acad. Sci., 1993, 695: 91-102. Murata, T. In vivo proton magnetic resonance spectroscopy study on premature aging in Down?s Syndrome. Biol. Psychiatry, 1993, 34(5): 290-7.